Interleukin-1 Receptor Antagonist Protein (IRAP) Therapy for Equine Osteoarthritis

IRAP, or Interleukin-1 Receptor Antagonist Protein, therapy is a novel approach at treating osteoarthritis (OA) in horses. It reduces the clinical signs of synovitis (inflammation of the joint lining) in horses without the potential side effects of corticosteroid administration. Prior to treating the affected joint(s), approximately 60mL of blood is drawn from your horse. The blood is processed over the next 24 hours, at which point the IRAP is ready to be injected into the affected joint(s). The joint is usually treated at various intervals depending on the condition for 3 or more treatments with 1-8mL per treatment depending on the size and location of the joint. Rest is typically recommended for at least 5-7 days following injection, per your veterinarian.


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